PIV Measurement of Fluid Flow Inside a Human Uterus Model for Cryoablation :: essays research papers

PIV MEASUREMENT OF FLUID spring INSIDE A HUMAN UTERUS MODEL FOR CRYOABLATIONXiaolong Luo1, Jim S.J. Chen1, Marla Wolfson2, Charles Philips2, Thomas Shaffer21Department of automatic Engineering, Temple University2Temple University School of MedicineAbstract A novel technique has been proposed that allows cryoablation to be achieved on the entire inner surface of the endometrium by circulate very cold perfluorochemical (perfluorocarbon) peregrine inside the human uterus. To understand the PFC flow field inside the uterus during cryoablation, a uterus deterrent example was constructed a fluid delivery system including the fluid delivery look into was designed and built to simulate the PFC flow during cryosurgery. With particle soma velocimetry (PIV), the fluid flow inside the uterus was investigated at room temperature to presentation a 2-D whole field velocity contour and vector plot.Keywords PIV, cryoablation, PFC, endometriumI. originationMenorrhagia is medically defined as excessive bleeding at menses, in duration or amount. A frequent cause of hypermenorrhea is uterine fibroid growth. Traditionally, hysterectomy is the main treatment for menorrhagia. Several cryosurgery methods such as localise cryoprobes 1 and balloon ablation 2 have been developed as alternatives to hysterectomy to treat the disfunction of the endometrium. However, these are localized techniques and sometimes there is still proliferation of the endometrium. A new technique is proposed that allows cryoablation to be achieved on the entire inner surface of the endometrium employ a PFC fluid 3. The objective of this project is to develop an economical treatment method for abnormal uterine bleeding by freezing the endometrium. It has been shown that a temperature of 30 &61616C is required for destroy tissue humiliation 4. The heat transfer process during cryoablation was investigated experimentally and numerically (1-D) with good proportionateness 5, in which a uniform fluid temperature boundary condition was use in the 1-D finite difference method to determine the temperature history in the human uteri of eight patients. This assumed that the fluid flow inside the uterus is uniform, repeatable and controllable. During the experiments it was found that the temperature difference at the inlet and outlet of the debut probe varied from 10C to 50C. Inconsistent fluid temperatures may be caused by inadequate circulation of PFC liquid, i.e., recirculation within the uterus. The refinement of this study is to understand the flow field inside the uterus colliery during cryoablation so that the desired flow field and uniform temperature field bum be obtained, thus proposing an optimal insertion probe design so that minimum PFC liquid and surgery time is used.